Preclinical models, metastasis, single cell approaches.
Affiliation: Georg Speyer Haus and Frankfurt Cancer Institute, Frankfurt am Main, Germany
Main scientific/ clinical interest: Characterisation of disease specific tumor microenvironments. Functional evaluation of tumor-niche dependencies in metastasis and hematological malignancies.
Techniques/ approaches you will contribute to RISEbrain: preclinical models, pre-clinical drug testing, RNA sequencing (bulk and single cell), multispectral flow cytometry
Most relevant awards & honors: EMBO YIP; ERC starting grant; José Carreras Career Award
VIB Ghent, Belgium
We are seeking a highly motivated postdoctoral fellow to join our international research team in Frankfurt. The successful candidate will use single cell technologies to explore the cellular and molecular drivers of local immune suppression in brain metastasis as well as carry out functional experiments using established animal models and patient-derived explant cultures, to uncover new means to overcome immune suppression and enable immune checkpoint therapy in this context. The ideal candidate should have experience in single cell approaches and an interest in performing wet lab experiments. Previous expertise with animal models or primary human samples is desirable but not mandatory.