Hind Medyouf

Preclinical models, metastasis, single cell approaches.

Affiliation: Georg Speyer Haus and Frankfurt Cancer Institute, Frankfurt am Main, Germany

Main scientific/ clinical interest: Characterisation of disease specific tumor microenvironments. Functional evaluation of tumor-niche dependencies in metastasis and hematological malignancies.  

Techniques/ approaches you will contribute to RISEbrain:  preclinical models, pre-clinical drug testing, RNA sequencing (bulk and single cell), multispectral flow cytometry

Most relevant awards & honors: EMBO YIP; ERC starting grant; José Carreras Career Award

Meet Hind Medyouf

News & Outreach*


Invited Speaker

European Macrophage and Dendritic cell society (EMDS) meeting

VIB Ghent, Belgium


Invited speaker

European Hematology Association Annual meeting

Frankfurt, Germany


Delegation member

EMBO India Research Partnership Tour



Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure. 


CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC


AXL inhibition in macrophages stimulates host-versus-leukemia immunity and eradicates naive and treatment resistant leukemia.

Cancer Discovery

Positions available*

Tumor niche evolution Group/ Cell-cell communication in the stem cell niche/ Georg-Speyer-Haus

We are seeking a highly motivated postdoctoral fellow to join our international research team in Frankfurt. The successful candidate will use single cell technologies to explore the cellular and molecular drivers of local immune suppression in brain metastasis as well as carry out functional experiments using established animal models and patient-derived explant cultures, to uncover new means to overcome immune suppression and enable immune checkpoint therapy in this context. The ideal candidate should have  experience in single cell approaches and an interest in performing wet lab experiments. Previous expertise with animal models or primary human samples is desirable but not mandatory.