Consortiumachievements*

Pre-RISEbrain*

Publications from each lab before the initiation of RISEbrain and in the last 5 years.

Growth exponents reflect evolutionary processes and treatment response in brain metastases

npj Systems Biology and Applications

Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours

Nature

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

Priego et al.
Nature Medicine (2018)

A clinically-compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.

Zhu et al.
EMBO Mol. Med.

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. 

Monteiro, Miarka et al.
Nature Medicine

A narrow-band multi-resonant metamaterial in near-IR

Materials 13 (22), 5140

A hybrid broadband metalens operating at ultraviolet frequencies

 Scientific reports 11 (1), 2303.

Mid-infrared narrow band plasmonic perfect absorber for vibrational spectroscopy

Sensors and Actuators A: Physical 301, 111757

Prophylactic transfer of BCR-ABL-, PR1-, and WT1-reactive donor T cells after T-cell-depleted allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia

Blood

Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer

J Immunother Cancer

Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer 

Immunity

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma”. 

Cancer Cell

Pan-cancer single cell RNA-seq identifies recurring programs of cellular heterogeneity

Nature Genetics

An integrative model of cellular states, plasticity and genetics for glioblastoma

Cell

Prognostic Characterization of Higher-Grade Meningiomas: A Histopathological Score to Predict Progression and Outcome.

Journal of Neuropathology & Experimental Neurology 2019 Mar 1;78(3):248-256

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

Acta Neuropathologica 2019 May;137(5):837-846

DNA methylation profiling discriminates between malignant pleural mesothelioma and neoplastic or reactive histological mimics.

The Journal of Molecular Diagnostics 2021 Apr 19:S1525-1578(21)00090-8

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure. 

Blood

CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

Leukemia

AXL inhibition in macrophages stimulates host-versus-leukemia immunity and eradicates naive and treatment resistant leukemia.

Cancer Discovery

During RISEBrain*

Publications from each lab through the RISEBrain 3 years project

Cracking the cancer-neuroscience connection

Drug Discovery News

Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma

Frontiers in Immunology

Tumor-targeted therapy with BRAF-inhibitor recruits activated dendritic cells to promote tumor immunity in melanoma

Journal for Immunotherapy of Cancer

Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche

Leukemia

Connections that drive science

EMBO Encounters

Invasive growth of brain metastases is linked to CHI3L1 release from pSTAT3-positive astrocytes

Neuro-Oncology (2024)

Living Biobank Of Brain Metastasis Samples Enabling ‘Personalized Medicine 2.0

Diagnostics World News

Updating cancer research with patient-focused networks

Trends in Cancer

Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits

Cancer Cell