Reverting immune suppressionto elicit brain metastasis control

About us*

The RISEbrain consortium brings together the highly complementary expertise of 6 teams with inter-sectorial (basic and clinical) and interdisciplinary focus (life sciences, computational sciences, engineering) to tackle the growing societal challenge posed by brain metastases.


RISEbrain brings together 6 partners with diverse backgrounds and expertise. Learn more about our team on our website.

Positions available*

We currently have job openings available! If you are interested check out our website for more information on how to apply.

Consortium achievements*

At RISEBrain, each laboratory has achieved significant scientific achievements in their respective fields of study. Visit our website to learn more about our achievements and ongoing research.

Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer

J Immunother Cancer

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. 

Monteiro, Miarka et al.
Nature Medicine

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

Priego et al.
Nature Medicine (2018)

Prophylactic transfer of BCR-ABL-, PR1-, and WT1-reactive donor T cells after T-cell-depleted allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia


Prognostic Characterization of Higher-Grade Meningiomas: A Histopathological Score to Predict Progression and Outcome.

Journal of Neuropathology & Experimental Neurology 2019 Mar 1;78(3):248-256

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

Acta Neuropathologica 2019 May;137(5):837-846

News & Outreach*

Our RISEbrain partners have been published and featured in top media outlets and conferences. Learn more on our website.


Clinical studies


A controlled, randomized, double-blind clinical trial to evaluate the efficacy of SILbinin versus placebo to prevent recurrence after surgical resection of a single brain METastasis from non-small cell lung carcinoma or breast carcinoma



SaxoCell: Development of theranostic target molecules for diagnosis and therapy

Funding Organisation: Federal Ministry of Education and Research


Nanotechnology: a portable device against cervical cancer


Grant for internationalization

Molecular dissection of ovarian cancer brain metastasis microenvironment through spatial transcriptomics

Project partners: Pathology unit, Department of Medical Sciences, University of Turin, Italy and Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College, London, UK

Amount: 55.481,46€


Invited Speaker

European Macrophage and Dendritic cell society (EMDS) meeting

VIB Ghent, Belgium


Invited speaker

European Hematology Association Annual meeting

Frankfurt, Germany